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The present study showed a non-significant change in the primary markers of erythroid mass (erythrocyte count, hemoglobin concentration, and hematocrit) in rats subjected to serial blood sampling via heart puncture, which may be explained by absence of hemorrhage after sample collection and the rapid erythroid regeneration process

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Rodriguez et al, 2004), although some notable exceptions have been reported (Bartel, 2018)

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