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Therefore, the complex comprising JAB1 and CRL4B may represent a potential oncogenic target in breast cancer, and the utilization of JAB1 inhibitors in conjunction with clinical chemotherapy drugs could potentially enhance the antitumor therapeutic efficacy

doi: 10.1186/s12937-025-01189-3, 158

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Stepwise 1,4-addition of the HCA to acrolein is followed by ring closure via 1,2-addition of the 2-imino group to the intermediate aldehyde (Fig

This master antioxidant plays a vital role in nutrient metabolism, antioxidant defence, and regulation of cellular activities such as protein synthesis and immune response