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9 A considerable amount of evidence suggests that glutathione depletion is an important risk factor for glaucoma

[DOI] [PubMed] [Google Scholar] 62.Barker RA, Studer L, Cattaneo E, et al

Its effectiveness may depend on: Dose Duration of use Product quality Baseline glutathione status Digestive and metabolic differences The outcome being measured Increasing a glutathione laboratory measurement does not automatically establish a clinical benefit, but the evidence does challenge the absolute claim that ordinary oral glutathione cannot be absorbed or used

It stabilizes cardiolipin and respiratory chain enzymes, reduces the production of ROS, and limits the formation of pathological mitochondrial supercomplexes

The ROS generation was detected with a Leica fluorescence microscope (Leica DM6000B) using Leica LAS X software, and quantitative analysis was performed with ImageJ software (version 1.60

doi: 10.1177/019262338701500219