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In another study, the SHRs with HHcy receiving folate at a dose of 0.4 mg/kg/day for 8 weeks showed a reduction in oxidative stress, as evidenced by decreased malondialdehyde (MDA) levels and increased superoxide dismutase (SOD) levels [77]
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Activation of the immune system and neuroinflammation The mRNA levels of proinflammatory cytokines and chemokines increase accompanied by OHP administration, and a strong correlation of this effect with the mechanical hypersensitivity development has been shown [81]
Archives of General Psychiatry
TMAO may be a potential biomarker of disease progression (219)
