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Lipid-based nanosystems, such as nanoemulsions and NLC, with or without in situ-forming hydrogel matrices, have been highlighted as effective approaches to achieve drug delivery from the nasal cavity to the brain
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Hydroxocobalamin shares the cobalamin molecular structure with cyanocobalamin
doi: 10.1038/srep08421
Deficiency of B12 occurs due to inadequate intake, decreased consumption of meat and dairy products, low intrinsic factor and malabsorption due to gastrectomy
