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For ESI+, the mass spectrometer settings were as follows: capillary voltage of 4500 V, nebulizer gas pressure of 2.0 bar, dry gas flow rate of 10 L min -1 , dry gas temperature of 220C, mass scan range of 50-1300 m/z, spectra acquisition rate of 10 Hz, and cycle time of 0.4 s
MsrA induction is foxo -dependent and persists for two weeks after cessation of the MetR diet

This deficiency can also be prevalent in heavy smokers and drinkers

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