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Accordingly, in IRI mouse model, simultaneous blockade of LPA1 and LPA3 receptors improves renal function, and the protective effect of the dual antagonist is reversed after the use of OMPT, an LPA3 agonist, suggesting that LPAR3 activation may promote renal injury in IRI [62]

Its upregulation of antioxidant enzyme expression, including superoxide dismutase and catalase, has also been a subject of research interest

Clinical characteristics, disease course, and outcomes of patients with acute generalized exanthematous pustulosis in the US

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G6PD deficiency reduces the amount of NADPH required for the formation of nitric oxide (NO) [34,35]

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