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Research Publications: Metabolic Studies Involving NNMT Inhibition Structural Analysis of Quinoline Derivatives

Because AOD 9604 has not completed the full clinical development pathway, its comprehensive side-effect profile in humans is not well characterised and should not be assumed to be benign
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Rotate between sites to prevent tissue changes from repeated use of one location

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Since mouse microbiome profiles often highly correlate with body weight and fat composition, this study was designed to test whether the cecal microbiomes of DIO mice treated with NNMTi and LD were comparable to the microbiomes of age-matched lean counterparts and distinct from microbiomes of DIO mice maintained on a high-fat Western diet (WD) or subjected to LD switch alone
