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Those products have a place in a skincare routine

Hrelec M, Klicek R, Brcic L, Brcic I, Cvjetko I, Seiwerth S, et al
Epub 2009 Sep 6
Missing or In-House-Only Testing: Why Its a Problem When testing is conducted exclusively in-house, there is no independent verification of results
Key ways it appears to mimic or amplify natural gastrointestinal and tissue repair mechanisms observed in animal studies: Strongly upregulates angiogenesis through multiple pathways (VEGF, EGR-1, FAK-paxillin) in injured tissues, similar to the bodys own response during normal wound healing and tendon/ligament repair

This includes tendons, ligaments, muscles, and skin