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Key Points Individuals with PSC have significant risk for developing hepatobiliary and colorectal cancers

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The Influence of the Gut Microbiome on the Neuronal Excitability of AH Neurons In addition to being regulated by enteroendocrine peptides and 5-HT, immune/inflammatory mechanisms, and neurotransmitters, the excitability of AH neurons can also be influenced by the gut microbiome and microbial mediators (FIGURE 5)

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Directions for Use: Initial Activation: Before using for the first time, prime the pump by pressing it firmly until a fine mist appears