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Interestingly, in this case, FAK inhibition only allowed melanoma cells with genetic resistance mechanisms to survive treatment, leading to more predictable resistance mechanisms and the absence of multi-drug resistance 43

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Experimental studies have demonstrated that the astragaloside-related enhancement of cell and organelle autophagy plays a pivotal role in the degradation and new synthesis of collagen I [26]

10.1038/ajg.2013.7 87 SoaresH
