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This comprehensive understanding, extensively discussed previously ( Furthermore, transcriptomic analysis applied to CTA revealed the activation of receptor-mediated pathways crucial for metabolic processes, facilitating both bioactivation and detoxification of chemicals

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The cholesterol synthesis pathway is also significantly altered in astrocytes from aged mice (24-months-old), likely contributing to the observed decline of cholesterol in the aged brain and potentially hindering production of myelin (Boisvert et al., 2018

Though deficiency for those starting out with adequate stores may take years to develop, the results of B12 deficiency can be devastating, with cases reported of paralysis, psychosis, blindness, and even death

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