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Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

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Selected AMPs in Different Stages of Clinical Trials

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KD ameliorated UC-induced intestinal barrier damage by inhibiting the overactivation of the PI3K/Akt/NF-B signaling pathway, attenuating the inflammatory response, including restoration of the intestinal villi and mitochondrial structure, and modulating the gut microbiota (increasing Alloprevotella , Treponema , Prevotella and Prevotellaceae , and decreasing Escherichia_Shigella and Desulfovibrio ) to optimize further the intestinal microenvironment (Liu et al., 2020)