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The F(ab)2 fragments are smaller than whole IgG molecules and better penetrate tissue for antigen recognition while avoiding unspecific binding to Fc receptors

[DOI] [PubMed] [Google Scholar] 350.de Las Heras N., Lahera V

Experimental approaches in this area often include second messenger analysis, such as cyclic AMP quantification, as well as kinase activation profiling and transcriptional response studies

May JM, Morrow JD, Burk RF
