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Utility of large-animal models of Bpd: chronically ventilated preterm lambs

At usual doses, NAPQI is quickly detoxified by conjugation, but in case of overdose this pathway becomes saturated and NAPQI accumulates, GSH is depleted and hepatic necrosis arises

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(2021) Homocysteine, folic acid, cyanocobalamin, and frailty in older people: Findings from the Invece.Ab study, Frontiers in physiology, [online] Available at: (accessed 7 th April 2022) Hamlin, J.C., Pauly, M., Melnyk, S., Pavliv, O., Starrett, W., Crook, T.A
PMID: 37 ThomasRLJiangLAdamsJSXuZZShenJJanssenSet al

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