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The presence of multiple RCD pathways ensures that when one death pathway is suppressed, others can compensate and function to maintain tissue and organ homeostasis

Food Chem Toxicol 69:182201 Rahman I, Biswas SK, Kirkham PA (2006) Regulation of inflammation and redox signaling by dietary polyphenols

Work from the Granneman group identified ABHD5 ligands that could stimulate lipolysis by bypassing receptor activation through the dissociation of ABHD5 from PLIN1 (48)

Elevated levels of serum Interleukin-8 (IL-8) in T1DM individuals with poor glucose control may contribute to an inflammatory response that has shown to lower IGF-1 levels in chronic inflammatory diseases [74]

Given the current lack of studies on VR-based interventions in SCD, future research should prioritize assessing their efficacy and long-term benefits, particularly in home-based settings in which early, preventive cognitive training could be most impactful