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Metabolic signature of ethanol-induced hepatotoxicity in HepaRG cells by liquid chromatographymass spectrometry-based untargeted metabolomics

Given their central role in cellular iron and redox metabolism, it is not surprising that mitochondria are potent modulators of ferroptosis 218

doi: Goel P, Jindal R, Singh T, Sharma S, Sharma P, Kaur H, Vohra K (2010) Focused Conference Group: Fc09-Inflammation And Immunopharmacology: New Tools For Old Diseases Role Of Ages Inhibitors In Inflammation And Rheumatoid Arthritis: Paper No.: 473

L., Ding, K., Liao, S

Curr Opin Immunol 76:102182

This suggests the hypothesis that the Semax/Cu 2+ complex mainly interacts with oligomeric species of A 140 by both retarding their formation and hampering their interaction with the lipidic membrane