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APX belongs to class I peroxidase family of proteins which are characterized by the presence of heme prosthetic groups

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They can continuously release therapeutic molecules in the body, thus solving the obstacles of traditional drug delivery methods and the insufficient exposure of drugs to the lesion sites [155]

APX1 has also been localized in the nuclei, together with SOD and CAT (Liu et al

Following its uptake, FOXO4-DRI reduced the number of senescence-induced FOXO4 foci, PML bodies and 53BP1 DNA-SCARS, while not affecting the number of small 53BP1 foci (Fig

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