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According to guidelines, the diagnosis of IPF can be considered definitive only in the presence of a surgical (not transbronchial) lung biopsy

FcR-mediated activation of neutrophils can stimulate NETosis 63,64

Elevated IL-1 levels in AH patients are closely linked to inflammation

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At the molecular level, overexpression of miR-21 inhibits 3-hydroxybutyrate dehydrogenase-2 (BDH2), leading to iron accumulation and enhanced activity of Fe 2+ -dependent TET enzymes

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