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Ulcerative Colitis (UC): Affects the colon and rectum , causing continuous inflammation along the intestinal lining, which can lead to ulcers, bleeding, and diarrhea

Science 235 , 481485 (1987)

Nonpharmacological Interventions Behavioral interventions to sustain a circadian rhythm in the sleepwake cycle, shift work and feeding have been proposed as efficient approaches to prevent or treat several chronic diseases [228]

Our patient was diagnosed with severe GSSD after neonatal onset, with symptoms including hemolytic anemia, hyperbilirubinemia and severe metabolic acidosis (intractable), urine-organic acid analysis results suggestive of the presence of 5-oxoprolinuria, and imaging results suggestive of central nervous system damage and developmental retardation in the infant at follow-up