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Zinc is very important for the functioning of the enzyme, hormone, and immune systems

Notably, in contrast to 23 (HA08), a structurally very similar epimer (HA09) which differs only with regard to one stereogenic center and exhibiting a 100-fold lower affinity to IRAP did not affect spine morphology, indicating a correlation between the capacity to inhibit IRAP and a positive impact on DSD and spine morphology

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Therefore, the observed decrease in gut luminal DCA abundance after VSG was not due to a reduction in substrate availability

Piredda, L