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First is whether the MRS based subtyping of patients could assist interpreting outcomes of future antioxidant trials in this illness

Andrews and colleagues (2009) demonstrated that MPTP-induced dopaminergic dysfunction is amplified in GHSR KO animals, and selective re-expression of GHSR1a in catecholaminergic neurons of GHSR KO animals reduced this degeneration

If you increase your dose to get results, you are also increasing your exposure to potentially impure substances

doi: 10.1128/IAI.00497-10 318 TakahashiH.WatanabeH.KimK

Ren J, Bharti A, Raina D, Chen W, Ahmad R, Kufe D

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