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This has been observed in many analytical-scale systems that use HPLC-type supports with particle sizes less than 10 m in diameter

Oral fucoxanthin (10 mg/kg) reduced experimentally UVB-induced skin pigmentation in guinea pigs, probably due to suppression of proinflammatory cytokine prostaglandin E2 (PGE2) synthesis and receptors involved in melanogenesis [85]

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Differential effects of IGF-binding proteins, IGFBP-3 and IGFBP-5, on IGF-I action and binding to cell membranes of immortalized human chondrocytes

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The metabolic syndrome: the crossroads between rheumatoid arthritis and cardiovascular risk
