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Disruption of sphingolipid metabolism leads to changes in the sphinganine to sphingosine ratio [114] as demonstrated in rat liver and mouse kidney at carcinogenic doses of FB1 [115]

In summary, the adaptive regulation of ROS homeostasis involves a complex network of mechanisms and signaling pathways

Conversely, fungal exosomes hold promise as vaccines: their specific components (e.g., mannan, glucan) can interact with TLR4 and Dectin-1 on immune cells, offering a potential strategy for combating or preventing candidiasis (Honorato et al., 2024)

The ANLS hypothesis proposes a coherent model where glutamate uptake by astrocytes stimulates their glycolysis, leading to lactate production and export, which is then taken up and oxidatively metabolized by neurons to meet activity-dependent energy demands (Brooks, 2018