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For example, a therapeutic serum concentration of 20 g per milliliter would fall above the threshold for treatment if the ingestion occurred more than 16 hours before the concentration was measured

10.1021/bi00201a009 7 AyalaA.MuozM

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In theoretical studies, both the sequence of amino acids (primary structure) and how those resulting polypeptides are orientated (secondary, tertiary, and quaternary structure) contributes to heterogeneous freezing 33,62,63

Impeding this crucial mechanism of energy production, bedaquiline is particularly effective against persistent bacilli (Sirturo, 2012