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Dual role of vitamin C on the neuroinflammation mediated neurodegeneration and memory impairments in colchicine induced rat model of Alzheimer disease

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Beta cell mass in diabetes: a realistic therapeutic target

Cys 2 ), cystine-free (Cys 2 -free), or cystine-free supplemented with GSH (750 M), CysGly (750 M), Fer-1 (10 M), or Trolox (100 M), and relative cell numbers were determined (n = 12 technical replicates from 3 independent experiments)

Buffer B, 95:5 water/acetonitrile with 0.2% ammonium hydroxide and 50 mM ammonium acetate for negative ionization mode

Furthermore, we detected the enzymatic activity and mRNA level of G6PDH (a crucial enzyme involved in the synthesis of NADPH) and found that although the mRNA level of G6PDH was lowered, PDLSCs in the HG group possessed a significant stronger enzymatic activity of cellular G6PDH ( Figure 2D )