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64 In serine proteases, neutrophil elastase (NE), cathepsin G and proteinase-3 destroy lung tissue by degrading ECM components, and induces epithelial cells and endothelial cells to release a variety of inflammatory factors to activate and chemoattract neutrophils to produce lung inflammation

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If you know you have MTHFR mutations, discuss B12 form with your prescriber and consider methylcobalamin if available