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[DOI] [Google Scholar] 51.Morley N., Clifford T., Salter L., Campbell S., Gould D., Curnow A

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For example, using the chronic unpredictable mild stress (CUMS) model, studies have demonstrated that specific Chinese medicines significantly improve depressive-like behaviors in animals

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The highly reactive nature of the active site cysteine, in a relatively exposed surface position, represents the major challenge because a reversible effective inhibitor should out-compete the high cellular concentration of glutathione