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The two molecules sit in the same melanocortin neighbourhood, but their receptor profiles, evidence bases, regulatory histories, and sourcing cautions are materially different

10.1124/dmd.31.7.908 [DOI] [PubMed] [Google Scholar] Chen, Y

Tirzepatide's adverse effect profile is well-characterized from extensive clinical trial data

Aug 15 2012;4(147):147ra111

Some stages are split further, using capital letters (A, B, etc.)

Bullous pemphigoid antigen II (BP180) and its soluble extracellular domains are major autoantigens in mucous membrane pemphigoid: the pathogenic relevance to HLA class II alleles and disease severity