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In female rats, an increase in the number of females with prolonged diestrus and a decrease in the mean number of corpora lutea resulting in a decrease in the mean number of implantation sites and viable embryos was observed at all dose levels
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But using them together can affect treatment results

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(2019) 7-Hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects
