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White blood cells also influence the early differentiation of bone and tendon progenitor cells, and specific PRF protocols can activate white blood cells (especially the monocytes and platelets in the leukocyte-rich matrix) to secrete endogenous growth signaling factors like BMP-2, BMP-7, FGF, VEGF, PDGF, TGF-Beta, and Thrombospondin, which are released locally over the next few days to weeks to accelerate and strengthen tissue repair, and these can further activate recruitment and differentiation of Mesenchymal Stem Cells (MSCs) as well as expression of several tissue remodeling genes

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One of the most significant immunopathologies involved in SARS-CoV-2 infection is cytokine storm, which has been identified as being a major cause of death in COVID-19 patients [16]

Thus, Quer, as an activator of the GSH system, is a promising natural small molecule for the treatment of cardiac injury