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Osteoporosis involves a gradual decline in osteoblasts and increased bone resorption by osteoclasts

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El-Dessouki AM, Alzokaky AA, Raslan NA, Ibrahim S, Selim H, Al-Karmalawy AA (2025) Dabigatran attenuates methotrexate-induced hepatotoxicity by regulating coagulation, endothelial dysfunction, and the NF-kB/IL-1beta/MCP-1 and TLR4/NLRP3 signaling pathways

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The tripeptide exists intracellularly either in an oxidised glutathione disulphide (GSSG) or reduced state (GSH), and maintaining an optimal GSH:GSSG ratio in the cell is critical for prevention of oxidative damage and for cell survival (Fig

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Collagen I accumulation can inhibit load-induced growth in mice 33 , perhaps due to the inability of critical transmembrane mechanosensors in muscle fibers (dystrophin, integrins) to adhere to laminin in the basement membrane 49,50

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The study evaluated the Minimum Fungicidal Concentrations (MFC) of CitAgNPs, which are critical for understanding the concentration required to achieve fungicidal activity [30]

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However, with the advancement of scientific knowledge the classification has also been shifted based on their selectivity for inhibiting cyclooxygenase/prostaglandin-endoperoxide synthase (PGHS) enzymes which are the major targets of these drugs

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