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When delta sleep is reduced, as it consistently is in depression, cortisol remains elevated through the night, growth hormone release is blunted, and inflammatory metabolites accumulate in the central nervous system
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Gating strategy was used for screening lymphocytes (FSC-A/SSC-A)

TRT is appropriate when a man has clinically low testosterone confirmed by blood work, combined with symptoms that impact quality of life

2021 Jul;70(7):1877-91
