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10.1056/NEJMcibr1402199 50

Nat Rev Immunol (2019) 19:47789

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however, this gradual increase was driven by individual edited cells that transitioned quickly from low to high heteroplasmy (Fig

The histological characteristics of AIH predominantly encompass extensive lymphocytic infiltration and the formation of rosette-like structures by hepatocytes, however, the precise mechanisms underlying these phenomena remain to be elucidated [216]