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Description
Synthetic versions can be derived from rooster combs or engineered in a lab, and there are a variety of proprietary formulations available

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Long-term depletion is now being linked with Alzheimers disease
Digestion can be performed in the glutathione buffer used to elute the protein from the affinity matrix provided there are no serine protease inhibitors in this buffer

Iron chelators such as DFO, DFP, VK28, and clioquinol bind free Fe + , forming stable complexes that limit iron toxicity

10.1038/s41573-021-00233-1 19 GadH.KoolmeisterT.JemthA
