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doi: 10.1038/nrdp.2016.80

[DOI] [PubMed] [Google Scholar] 240.Sawicka AK, Renzi G, Olek RA

In the cell, glutathione is used to reduce the sulfene groups in the protein molecule (Pt-SOH), which are formed during the oxidation of the SH groups of cysteine residues

A randomised controlled trial published in Clinical Infectious Diseases demonstrated that Thymosin Alpha-1 treatment in severe COVID-19 patients reduced 28-day mortality by 30% compared to standard care alone.17 While this was acute disease, not long COVID, it confirms the biological plausibility of the immune mechanism

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4 Molecular mechanism of intestinal barrier damage 4.1 TLR signaling pathway Toll-like receptor (TLR) is an innate immune pattern recognition receptor, promptly triggering intracellular signaling cascades upon detection of pathogen-associated molecular patterns (PAMPs), including proteins, nucleic acids, and lipids derived from invading pathogenic microorganisms