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However, safety depends on several factors: injection site rotation to avoid lipodystrophy, adequate hydration (both agents can increase fluid demand), and monitoring of B vitamin status since semaglutide may affect nutrient absorption slightly during rapid weight loss phases

Numerous studies in the sports field have shown that doses ranging from a few hundred milligrams to 10 g daily, both with single and chronic administration, result in a general improvement in the athletes energy metabolism and an increase in performance

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