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For example, the immature kidney may be resistant to amino-glycosides (Marre et al., 1980) and cephalosporins (Tune, 1975), but the reverse is true for other chemicals such as hexachlorobutadiene (Hook et al., 1983)

Serious but rare complications include pancreatitis, gallbladder disease, and acute kidney injury

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A range of compounds emitted by CAFs, such as vascular endothelial growth factor A (VEGF-A), is noted to play a role in the stimulation and sustenance of T regulatory (Treg) cells, either directly or indirectly [46]

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