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GSH actively attends to oxidative free radicals and, in doing so, becomes oxidized and converts to the inactive GSSG

Blocking the transferrin receptor with specific antibodies reduced intracellular iron levels, suppressed inflammatory T cell activity, and enhanced regulatory T cell activity

Prognostic significance of differentially expressed miRNAs in esophageal cancer

Glutathione, an endogenous antioxidant The GST enzymes conjugate (bind) an antioxidant called glutathione to the substance for elimination

Yanagita: Japan Agency for Medical Research and Development (JP24gm0010011, JP19gm1210009, JP21zf0127003, JP22ek0310020, and 21lm0203006), Japan Science and Technology Agency (JPMJSF2315), and Japan Society for the Promotion of Science (JP20H03697, JP23H02925)

To complement ROS quantification, we measured intracellular levels of reduced GSHthe principal cellular antioxidantusing the mBCl fluorescent probe and flow cytometry using the same treatment plan (Figure 3A)