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When used appropriately under medical supervision, B12 injections are generally considered very safe

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AOD-9604 across its full clinical program had no single serious adverse event attributed to the compound

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The suppressed-3-AR phenotype that AOD-9604 appeared to normalize in obese rodents may not carry the same weight in human adipose physiology

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Additionally, high levels of homocysteine may accumulate due to B12 deficiency

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All controlled studies referenced below were conducted in cell culture (3T3-L1 adipocytes, primary muscle stem cells) or rodent models (diet-induced obese mice, aged C57BL/6J mice)

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