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Chandys hypothesis that a sudden influx of B12 can trigger repair processes

Whereas, LD 50 in rats was found to be 57.5 mg/kg (45.6-69.4) and 794.3 mg/kg (469.8-1 118.8) after intra-peritoneal injection and oral ingestion respectively

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If you happen to delve into the research on B12 deficiency, be sure youre looking closely at how the study defined deficiency, insufficiency, and normal levels

In addition, combined PI3K/mTOR and ERK inhibition can reverse therapeutic resistance in ovarian cancer cell lines, but the clinical efficacy of these agents requires further preclinical determination [228]

A significant increase (25%) in microsomal lipid peroxidation was observed in both liver and kidney of diabetic rats (Figure 1C)