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These investigations contribute to broader scientific research into peptide fragment biology

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Biomarkers normalise more rapidly than an improvement or reversal of (neurological) symptoms

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Metabolic health and insulin sensitivity NNMT activity climbs in the fat tissue of people with obesity and type 2 diabetes, which is exactly why the enzyme drew interest as a target for metabolic syndrome in the first place

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Liver, kidney and allergic reactions have been reported with other forms (NOT methylcobalamin) of B12

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What they did: Obese mice received AOD-9604 orally (via gavage) for 14 days at various doses (50, 250, 500 g/kg)

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Segerlantz M, Bramnert M, Manhem P, Laurila E, Groop LC

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