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The purified OX2 was buffer exchanged into a final formulation buffer at a protein concentration appropriate to downstream applications

In total, 8590% of ALS cases are sporadic, occurring without known genetic cause or family history

However, the recycling process of BH4 requires the participation of dihydrofolate reductase (DHFR)

In the high-resolution XPS spectrum, peaks at 164 eV and 158.65 eV confirmed the presence of Bi 3+ in the KBiF 4 nanoclusters (Fig

The guide cannula was held in place using UV-cured cement (G-bond and G-aenial Universal Flo, GC), and a dummy cannula (PlasticsOne, C315DCS-4/Spc, 2.5 mm) was inserted into the guide cannula to keep the cannulation closed until and in between compound infusions

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