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10.1007/s12011-020-02342-1

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Nrf2 as a potential mediator of cardiovascular risk in metabolic diseases

The key pathological features of ALS include the loss of pyramidal Betz cells in the motor cortex, anterior horn cells in the spinal cord, and lower cranial motor neurons [179]

Five mitochondrial enzymes are known to require lipoylation for catalysisthe PDHc, 2-oxoglutarate dehydrogenase complex (OGDHc), 2-oxoadipate dehydrogenase complex (OADHc), branched-chain -ketoacid dehydrogenase complex (BCKDHc) and the glycine cleavage system complex (GCVc)