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Their mechanisms diverge on several key fronts: GHK-Cu has documented antioxidant effects and MMP/TIMP modulatory activity, while retinoids primarily drive epidermal turnover and reduce UV-induced MMP activation
In general, chelation therapy is recommended for children only in cases where blood lead levels are 45 g/dL or greater
To address these challenges, various strategies including PEGylation 20 , glycosylation 21 , lipidation 22 , and protein fusion 3 have been developed
Phototherapy This treatment modality remains an essential tool for the management of all kinds of vitiligo
