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15 At higher doses, Lcarnitine is metabolized to trimethylamine and butyrobetaine

This was followed by an upregulation of pro-apoptotic markers P53 and caspase-3, which clearly reflects SIRT1s negative regulatory role

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(2011): L-carnitine--metabolic functions and meaning in humans life
doi: 10.1016/j.ijsu.2020.04.018
