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RussellLBroderickGTaylorRFernandesHHarveyJBarnesZet al
Edaravone Edaravone, approved in Japan (2015) and the US (2017), represents another major pharmacological option, particularly indicated for early-stage ALS (23)

Br J Psychiatry (1991) 158:50310

Microglia release activators of neuronal proliferation mediated by activation of mitogen-activated protein kinase, phosphatidylinositol-3-kinase/Akt and delta-Notch signalling cascades

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93 These findings illustrate the central role of exosomes in promoting stromal renewal through synchronized modulation of proliferative and anti-apoptotic signaling
