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The data (Figure 3A) suggested a modest rise (~ 15%) in mean activity among replicate samples, but the sample-to-sample variation was large enough that statistical significance was not achieved ( p = 0.57)

Significant changes in leptin, which is regarded as a special body weight regulating hormone, were also noted (29), meaning that the resistance to leptin is partly improved in obese subjects

Consistent with this, Yashiro et al

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Regulation of the pyruvate dehydrogenase complex
