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The former refers to the prevention of AF by controlling risk factors such as diabetes, hypertension, and heart failure before AF occurs, and the latter mainly refers to targeting ion channels, inflammation, oxidative stress, and other pathways to reduce or reverse atrial electrical and structural remodeling, reduction of AF load, and reduction of the chance of AF occurrence or progression

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Int J Biol Macromol 181:890904

Fecal stercobilinogen is also increased in the stool

Superoxide radicals (O 2 ), a type of ROS generated during metabolic processes, are converted into H 2 O 2 and O 2 by SOD, using metal as a cofactor (187)