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10.1124/jpet.108.140301 Summary Keywords oxidative stress, reactive oxygen species, inflammation, diabetes mellitus, ischemiareperfusion injury, mitochondria, transient receptor potential channels Citation Wang M, Liu Y, Liang Y, Naruse K and Takahashi K (2021) Systematic Understanding of Pathophysiological Mechanisms of Oxidative Stress-Related ConditionsDiabetes Mellitus, Cardiovascular Diseases, and IschemiaReperfusion Injury

Uncoupled endothelial NOS, nicotinamide adenine dinucleotide phosphate hydrogen (NADPH) oxidase, xanthine oxidase, and mitochondrial electron transport are the main sources of ROS

Normalised values of all metabolites detected are presented in Supplementary Data 3

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